Pee Dee Equality

Website: https://www.peedeeequality.org/
Address: Florence, South Carolina
Email: peedeeequality@gmail.com
Description: Established in 2022, they support programs that demonstrate collaboration among multiple organizations in support of LGBTQIA+ initiatives. Pee Dee Equality is the organizer of the Pride in the Pee Dee festival.

United Ministries

Website: https://united-ministries.org/
Address: 606 Pendleton St Greenville, SC 29601
Email: info@united-ministries.org
Description: Serves Greenville community members experiencing scarcity of resources. They have several programs, including Place of Hope which provides basic services to the unhoused and case management, emergency financial assistance, adult education, emergency shelter housing, and an economic mobility program. They also offer computer tutoring, computer lab access, mental health counseling, a matched savings program, and incentives for completing goals.

Place of Hope: (864) 232-6463

Emergency Assistance: (864) 336-2661

Adult Education: (864) 335-2604

Emergency Shelter Housing: (864) 271-3424

Striving to Thrive: (864) 605-7696

Youth OUTLOUD

Website: https://www.harriethancockcenter.org/programs/youthoutloud
Address: 1108 Woodrow St, Columbia, SC, 29205
Phone: (803) 771-7713
Description: A group for LGBTQ+ youth in grades 6-12. They aim to promote open discussion and dialogue in a space where experiences can be shared and meaningful connections can be developed. Their vision is to transform safe spaces of support into brave spaces for action. By developing youth leadership and creating opportunities for youth-led initiatives, they aim to empower young leaders to build a strong community for themselves and for others in the Midlands and beyond. Middle school meets on the 2nd and 4th Sundays from 5-7pm. High school meets on the 1st and 3rd Mondays from 6-8pm. Dinner is always provided.

Caregivers of LGBTQ+ Youth

Website: https://www.harriethancockcenter.org/programs/peer-support
Address: 1332 Main Street, Unit #120, Columbia, SC, 29201
Phone: (803) 771-7713
Description: This group is a peer-support group for all caregivers/parents of LGBTQ+ youth. The group aims to provide an environment to learn about the unique experience of caring for someone who identifies as LGBTQ+ and how to better support/affirm them. This group meets during the first Youth OUTLOUD meeting (the 2nd Sunday of the month) at Queer Haven Books from 5-7 PM. No registration required.

Queer x Disabled

Website: https://www.harriethancockcenter.org/programs/peer-support
Address: 1108 Woodrow St, Columbia, SC, 29205
Phone: (803) 771-7713
Description: The group aims to provide information, opportunities, and support for queer disabled folx by giving everyone the chance to make social connections and discuss experiences being both LGBTQIA+ and disabled in the area. We welcome everyone no matter the disability. Open to anyone with visible and non-visible disabilities, mental health and neurodivergent needs, and friends/family of those who may need assistance. This group is held every first Wednesday from 6-8pm. Ages 18+, no registration required.

Queer x BIPOC

Website: https://www.harriethancockcenter.org/programs/peer-support
Location: 1108 Woodrow St, Columbia, SC 29205
Contact: (803) 771-7713
Description: Safe, inclusive space for queer individuals of color to connect, share experiences, and find solidarity. Meets 2nd and 4th Fridays, 7–9 PM. No registration required.

Transfusion

Website: https://www.harriethancockcenter.org/programs/peer-support
Location: 1108 Woodrow Street, Columbia, SC 29205
Contact: (803) 771-7713
Description: Peer-led, non-clinical support group for transgender and gender non-conforming/nonbinary adults. Meets every 3rd Wednesday, 6–8 PM. No registration required.

Queer Wellness Center

Website: https://www.queerwellnesscenter.org/
Location: 30 Pointe Circle, Greenville, SC 29615
Contact: info@queerwellnesscenter.org | (864) 655-5193
Description: Provides a safe, affirming environment in Upstate SC with programs like BLOOM (LGBTQ+ competency training and free therapy for youth/families), LEAP (peer support for trans community), AFFIRM SC (professional training), and Project HEART (affirming medical care). Offers scholarships for medical visits and housing.

The Ladies Room SC

Website: https://www.theladiesroomsc.org/home
Location: Upstate, SC
Contact: ebonisims14@gmail.com
Description: The first Black-led, trans-led LGBTQ+ center in Upstate SC serving primarily Black and Brown trans and nonbinary people. Offers skill programs, HRT and name change assistance, STD/STI/HIV services, addiction support, holistic healthcare, emergency housing, food assistance, and more.

Lowcountry in Transition

Website: https://www.charlestontranscommunity.org/
Location: Charleston, SC
Contact: lowcountryintransition@gmail.com
Description: A group by and for trans and nonbinary adults supporting each other through community building, support and social events, and resource sharing. Monthly meetings occur 1:00–2:30 PM on the 4th Saturday, with additional online and in-person events.

Camp Lightbulb

Website: https://www.camplightbulb.org/
Location: New York City or Los Angeles
Contact: info@camplightbulb.org | (323) 484-7993
Description: LGBTQ+ summer camp for youth ages 14 to 18. Since 2011, they have welcomed over 2,500 youth nationally and internationally. Camps incorporate principles of art, community, fun, learning, outdoors, service, and wellness. Financial assistance and pay-what-you-can payment plans are available.

Give Us The Floor

Website: https://giveusthefloor.org/
Description: A US-based nonprofit providing 2SLGBTQIA+ youth across the US with a supportive, safe, and anonymous online community via a free mobile app. Trained youth facilitate group chats that help break cycles of isolation and shame, addressing mental health and social issues such as depression, anxiety, identity, discrimination, bullying, relationships, domestic violence, and body image. While specializing in Queer and Trans youth support, all allies are welcome to join.

Uplift Outreach Center

Website: https://upliftoutreachcenter.org/
Location: Spartanburg, SC
Contact: upliftoutreachcenter@gmail.com | (864) 381-7234
Description: Providing a safe space where youth are accepted and partnering with local organizations to provide LGBTQ+ specific resources to our community. They offer support, increase self-advocacy and culturally competent services to decrease suicide and suicidality. They promote tolerance and acceptance while welcoming and encouraging other community members and organizations to participate in their mission of supporting LGBTQ+ youth and their straight allies. Uplift Outreach Center is located behind Fernwood Baptist Church off of Greengate Lane. They are within walking distance of the SPARTA Hillcrest bus route. The Center is now open a few afternoons a week to youth up to age 23. Please call for current open hours.

Forge

Website: https://forge-forward.org/
Contact: (414) 559-2123
Description: Forge's work is trauma-informed, research based and empowerment-focused. They provide training & technical assistance for professionals who work with transgender individuals. Find resources & support for service providers and transgender and non-binary individuals, survivors of violence, family and friends. They foster connection & awareness building healthy relationships and interactions with the general public.

Pride Myrtle Beach

Website: https://pridemyrtlebeach.org/
Location: Myrtle Beach, SC
Contact: (843) 839-2052
Description: Pride Myrtle Beach is the primary and most active organization advocating for the Myrtle Beach area LGBTQ+ community. Collaborating closely with community organizations, medical providers and local government, they provide easy access to essential services such as medical care, HIV testing and prevention, and educational opportunities. They are also host to a number of cultural events, family spaces, and festivals, including the June Pride Month Picnic and the Myrtle Beach Pride in the Park Festival, drawing thousands of visitors each year. Through their inclusive approach and diverse offerings, Pride Myrtle Beach celebrates and empowers all members of the LGBTQ+ community, ensuring they feel supported and valued year-round.

Black Educated Lesbians

Website: http://blackeducatedlesbians.com
Contact: admin@blackeducatedlesbians.com
Description: Black Educated Lesbians (BEL) is a global nonprofit organization supporting Black queer women through mentorship, leadership development, economic empowerment, and community building. Founded in 2014, BEL provides tools for professional growth and social advocacy.

Alliance For Full Acceptance (AFFA)

Website: https://www.affa-sc.org/
Contact: info@affa-sc.org | (843) 883-0343
Address: 3265 N. Carolina Avenue Suite 202, North Charleston, SC 29405
Description: The Alliance For Full Acceptance (AFFA) is a Charleston-based nonprofit working to achieve, nurture, and defend equality and full acceptance for LGBTQ+ people in South Carolina. AFFA builds partnerships and advocates for awareness, protections, and equality. AFFA Action is its 501(c)(4) sibling focused on legislative advocacy and political action.

Bisexual Resource Center

Website: http://biresource.org/
Contact: brc@biresource.org
Description: The Bisexual Resource Center provides support for the bisexual community and raises public awareness about bisexuality. Their vision is a world where love is celebrated regardless of sexual orientation or gender expression.

Harbor Camps

Website: https://harborcamps.org/our-story/
Contact: (781) 400-1617
Description: Harbor Camps, formerly Camp Aranu’tiq, was the first summer camp specifically for transgender and non-binary/gender-nonconforming youth. Their mission is to build confidence, resilience, and community through immersive camp experiences, ensuring accessibility regardless of financial need.

Campaign for Southern Equality

Website: https://southernequality.org/
Contact: (828) 242-1559
Description: The Campaign for Southern Equality is working to build a South where LGBTQ people are equal in every part of life. Their work includes the Legal Equality Project, the Southern Equality Fund empowering LGBTQ leaders, and a Community Health Program offering services and resources for LGBTQ Southerners.